Hyperlipidemia refers to elevated levels of lipids (fats) in the blood, including cholesterol and triglycerides. These lipids play vital roles in the body, such as providing energy and forming cell membranes. However, when lipid levels are too high, they can contribute to the buildup of fatty deposits (plaques) in the arteries, increasing the risk of cardiovascular diseases like heart attack and stroke.

Familial Combined Hyperlipidemia (FCHL)
Familial combined hyperlipidemia (FCHL) is a specific type of hyperlipidemia that is inherited, meaning it runs in families. This condition involves a combination of:

  • High levels of low-density lipoprotein (LDL) cholesterol, often referred to as “bad” cholesterol.
  • Elevated triglycerides, another type of fat in the blood.
  • Normal or slightly reduced levels of high-density lipoprotein (HDL) cholesterol, known as “good” cholesterol.

FCHL is one of the most common genetic lipid disorders and is a significant risk factor for premature cardiovascular disease.

Causes of FCHL
FCHL is caused by a combination of genetic and environmental factors:

  • Genetics: The disorder is inherited in an autosomal dominant pattern, meaning that having one copy of the altered gene from either parent is enough to cause the condition. Multiple genetic variations may contribute to its development, including those affecting lipid metabolism.
  • Lifestyle Factors: While the condition is genetic, factors such as diet, physical activity, smoking, and obesity can exacerbate lipid abnormalities.

Symptoms of FCHL
FCHL itself often does not cause symptoms, but the associated risks of cardiovascular disease can manifest as:

  • Chest pain or discomfort (angina).
  • Symptoms of a heart attack, such as shortness of breath or pressure in the chest.
  • Xanthomas: Fatty deposits under the skin, although these are less common in FCHL compared to other lipid disorders.

Diagnosis of FCHL
Diagnosing familial combined hyperlipidemia involves:

  • Lipid Profile Testing: Measures levels of LDL, HDL, total cholesterol, and triglycerides in the blood.
  • Family History: Identifying patterns of high cholesterol, triglycerides, or early cardiovascular events in relatives.
  • Genetic Testing: May help confirm the diagnosis in some cases.

We are currently servicing all states and Guam except for California.

OPENING HOURS

  • Monday 8:30AM - 5PM
  • Tuesday 8:30AM - 5PM
  • Wednesday 8:30AM - 5PM
  • Thursday 8:30AM - 5PM
  • Friday 8:30AM - 5PM
  • SaturdayON CALL
  • SundayON CALL